We hope you will enjoy this networking opportunity!

External academic guests:

Michelle Arkin, Distinguished Professor of Pharmaceutical Chemistry at UCSF.
Ramiro Alejandro Tomasi, Assistant Professor of Buccal Pathology at National University of Cordoba, Argentina.
Tyler Johnson, Associate Professor of Natural Sciences and Mathematics at Dominican U of CA.
Joseph Morris, researcher in the lab of Tyler Johnson at Dominican U of CA)
Mary West, Core Facility Director for the Cell and Tissue Analysis Facility (CTAF) and High-Throughput Screening Facility (HTSF).
~~Attn: CSC trainees…The HTSF is recruiting to hire a new screening facility manager!~~
Pingping He, Core Facility Manager for the High-Throughput Screening Facility (HTSF).
Deepa Sridharan, Project Scientist for the High-Throughput Screening Facility (HTSF).

Industry guests:

Maddalena Adorno, CEO & Co-Founder at Dorian Therapeutics. LinkedIn
Asheley Bailey, Advanced Technology Account Executive at CDW. LinkedIn
Rachel Bright, Alliance Management and Business Development at Gilead Sciences. LinkedIn
Alix Chan, Lead Scientist at Genentech. LinkedIn
*Paul Fielder, Vice President of Biomarker Development at Genentech. LinkedIn
*David Greenberg, Account Manager at Axion Biosystems. LinkedIn
Maureen Hillenmeyer, CEO & Founder of Hexagon Bio, Inc. LinkedIn
Kelly Huggins, Director of Technology & Strategic Alliances, Therapeutic Discovery at Amgen. LinkedIn
*Tannia Lau, Research Scientist, Genetic Medicine at Eli Lilly. LinkedIn
Gabriel Mitchel, Senior Innovation Scholar, Novartis Institutes for BioMedical Research (NIBR). LinkedIn
Gregory Notte, Executive Director of Medicinal Chemistry at Gilead. LinkedIn
*Cameron Pye,Co-Founder at Unnatural Products. LinkedIn
Francesco Rubbo, Staff Machine Learning Scientist at Spring Discovery. LinkedIn
*Josh Schwoshert, Co-Foudner at Unnatural Products. LinkedIn
Shuhei Tomimoto, Sr. Manager at Ono Pharmaceuticals. LinkedIn

*=UCSC Alum

Vendor tables:

Agilent Technologies
Diana Bogorodskaya, Sales & Business Development. LinkedIn

PerkinElmer
Marc Guerra, Sales Specialist, In Vivo. LinkedIn
Chananat Klomsiri, Sr. Discovery Reagent Sales Specialist. LinkedIn
Bill Ortiz, Principal Sales Specialist, plate readers. LinkedIn

BioLegend (affiliated with Perkin Elmer)
Anisha Madhav. LinkedIn
Robert Adams, Sr. Marketing Coordinator – Trade Shows and Events. LinkedIn

UCSC Faculty attending:

Chemistry and Biochemistry
Phillip Crews, Chem Biochem (emeritus)
Timothy Johnstone
Joseph Konopelski (emeritus)
Scott Lokey, Chem Biochem & Faculty Director of the CSC
John MacMillan, Chem Biochem & VCR
Glenn Millhauser, Chem Biochem & Dept Chair
Seth Rubin, Chem Biochem
Laura Sanchez, Chem Biochem

Molecular, Cellular, and Developmental Biology
Bradley Colquitt
Sharma Upasna
Martha Zuniga

Microbiology and Environmental Toxicology
Vicki Auerbuch Stone, Assoc Faculty Director of the CSC
Karen Ottemann
Michael Patnode

Engineering
Angela Brooks
Daniel Kim
Shelbi Russell
Ali Yanik, Electrical & Computer Engineering

Earth & Planetary Sciences Department
Paul Koch, PBSci Dean

And many more registrants!

10 AM REGISTRATION

Coffee available in the Bojwani room. Come check out the vendor tables in the Rotunda: Perkin Elmer, Agilent/BioTek, and BioLegend.

10:30-12:30 MORNING SESSION

10:30 AM Land acknowledgement, Vicki Auerbuch Stone, Professor of Microbiology & Environmental Toxicology and CSC Associate Director. Click for more info about the land acknowledgement.

10:31 AM Welcome, Glenn Millhauser, Head of Chemistry & Biochemistry Department

10:35 AM Opening plenary, Scott Lokey, Professor of Chemistry & Biochemistry and Faculty Director of the CSC
“UCSC CSC – a Rich and Varied History”

11:00 AM Tools & technologies update, Beverley Rabbitts, CSC Director of Operations
“Welcome to a New Era at the Fully Revamped CSC”

11:15 AM Research in progress: Jaru Taechalertpaisarn, CSC user from Scott Lokey’s lab
“Discovery of Novel Active Macrocyclic Peptides Through Permeable-First Perspective”

11:30 PM Research in progress: Aswad Khadilkar, CSC user from John MacMillan’s lab
“Assigning Mechanism of Action To Natural Products In Multiple Biological Contexts Using Gene Expression And Phenotypic Screening Methods Established By The HIFAN Program”

11:45 AM Morning keynote, Maureen Hillenmeyer, Founder and CEO of Hexagon Bio
“From academia to biotech startup: Launching a drug discovery company using new approaches in computation and automation”

12:30-1:30 PM NETWORKING LUNCH AND POSTER SESSION

12:30-1:00 PM First session – Poster presenters with last names A-L:
Abrams, Cech, Dzhanbekova, Hosseinzadeh, Hug, Jacobson, Johnson, Khadilkar, Liang, Lohith

1:00 PM-1:30 PM Second session – Poster presenters with last names M-Z:
Morris, Mitchell, Mueller, Ngoi, Rabbitts, Rubbo, Sharma, Taechalertpaisarn, Wijeratne, Yang

1:30-3:30 AFTERNOON SESSION

1:30 PM Invited faculty talk: Phil Crews, Distinguished Professor of Chemistry & Biochemistry
“Sponge Derived Molecule Discovery, Adventures of The Three Amigos Using the UCSC CSC”

2 PM Research in progress: Cindy Liang, CSC user from Angela Brooks’s lab
“Pairing Phenotypic Assays with Direct RNA Sequencing to Understand U2AF1 S34F and Cigarette Smoke’s Functional Role in Lung Cancer”

2:15 PM Research in progress: Gerd Mueller, CSC user from Seth Rubin’s lab
“Mechanisms of cell cycle-dependent gene regulation”

2:30 PM Presentation from our sponsor, Robert Graves, Field Applications Scientist, Perkin Elmer
“Phenotypic profiling by Cell Painting and fast confocal imaging with the Opera Phenix Plus High-Content Screening System”

2:35 PM Expression of gratitude, poster prizes, and awards, Beverley Rabbitts and Scott Lokey

2:40 PM Afternoon keynote, Michelle Arkin, UC San Francisco
“Looking for the Middle Way – Innovation and Application in Academic Drug Discovery”

3:25 PM Closing remarks, Paul Koch, Distinguished Professor of Earth & Planetary Sciences and Dean of the Division of Physical & Biological Sciences

 

Our industry sponsors will have the following vendor tables available throughout the day for education and networking:

PerkinElmer High Content, reagents and supplies, automation, plate readers, and bioinformatics (3 tables).

BioLegend Antibodies, proteins, and kits (1 table).

Agilent BioTek liquid handling (1 table).

We also thank our symposium sponsors at UCSC: the Office of Research; the PBSci Division Dean’s Office; Department of Chemistry & Biochemistry; Department of Molecular, Cellular, and Developmental Biology; Department of Microbiology and Environmental Toxicology; and the Biomolecular Engineering department within Baskin Engineering.

We also would like to thank the following supporters of the Chemical Screening Center: the Santa Cruz branch of the California Institute for Quantitative Biosciences (QB3) and the UCSC Physical and Biological Sciences Division. We are grateful for their ongoing financial support for our daily operations, which supplements user fees to keep our staff paid and our instruments running!

We’re excited about our upcoming UC Santa Cruz Chemical Screening Center Grand Reopening Celebration and Research Symposium! Please have a look at the formal invitation, which includes a link to register. We also have a link where anyone can make a voluntary donation to the symposium fund. The symposium will be aimed at a general scientific audience, but all are welcome to attend. And we have a link where you can buy merchandise with our symposium theme art!

Calling all presenters: If you want to apply to give a poster and/or talk, please fill out a very brief form with your presentation title by April 15. We have slots for 5 faculty talks and 5 trainee talks, as well as lots of room for posters. It will be exciting to see all the projects using our resources in one place and have some stimulating discussions. There will be prizes! The full agenda will be made available once we have the talk titles so please send yours ASAP.

 

We have 2 amazing guest speakers lined up, not to be missed!

The opening plenary:

Maureen Hillenmeyer, PhD

CEO and Founder
Hexagon Bio

The closing plenary:

Michelle Arkin, PhD

Distinguished Professor and Chair of Pharmaceutical Chemistry, UC San Francisco
Director, UCSF Small Molecule Discovery Center

Questions? Please email Beverley Rabbitts.

We have two new commercial libraries to offer! 8,387 known bioactives (includes FDA-approved for repurposing) from TargetMol, in the form of 27 384-well plates (pictured to the left), and 64,000 synthetic drug-like diversity compounds from ChemDiv, in the form of 200 384-well plates (pictured to the right). Stay tuned for our daughter plating progress, which we will do using our PlateStacked Janus MDT 96-channel pipettor into Echo-compatible low-dead-volume cyclic olefin plates.

This week, we’re excited about two talks by CSC users that will showcase application of our technologies to interesting research projects! Congratulations to Sahar and Laura on the success of your projects!