CSC Current Members:
- R. Scott Lokey, PhD
Faculty Director
Lokey Lab website
Profile - Vicki Auerbuch Stone, PhD
Associate Faculty Director
Auerbuch-Stone Lab website - Beverley M. Rabbitts, PhD
Director of Operations
Profile - Matylda Zietek, MSc
Screening Specialist for Lokey & Yildiz labs
Profile - Current CSC undergrad interns:
Kenny, Stephanie, Aria, Lucy, Georgina, Marissa
Our Affiliation:
Chemical Screening Center
Department of Chemistry and Biochemistry
Division of Physical and Biological Sciences
University of California, Santa Cruz
People affiliated with the CSC, past and present:
Listed alphabetically.
Internal Advisory Committee:
- Doug Kellogg
Professor in Department of Molecular, Cell, and Developmental Biology - Paul Koch
Dean of the Division of Physical and Biological Sciences - Scott Lokey
Professor in Dept. of Chemistry & Biochemistry
(non-voting) - Vicki Auerbuch Stone
Professor in Microbiology & Environmental Toxicology Department & Biochemistry
(non-voting) - Glenn Millhauser
Chair of the Committee
Professor in Dept. of Chemistry & Biochemistry - Karen Ottemann
Professor in Department of Microbiology and Environmental Toxicology - Ted Holman
Professor in Department of Chemistry & Biochemistry
External Advisory Board:
- Michelle R. Arkin
UCSF Distinguished Professor and Chair of Pharmaceutical Chemistry
Co-Director of the Small Molecule Discovery Center - Roger G. Linington
Simon Fraser University Professor of Chemistry
PI for Center for High Content Functional Annotation of Natural Products
Canada Research Chair in High-Throughput Screening and Natural Products Discovery - Ian Pass
Sanford Burnham Prebys Center for Chemical Genomics Director of High-Throughput Screening
Team Lead of Chemical Biology - Joshua Schwochert
Co-Founder and Chief Scientific Officer at Unnatural Products - Mary G. West
UC Berkeley Facility Director of Shared Stem Cell Facility and High-Throughput Screening Facility
Listed alphabetically:
- Phil Crews
- Ted Holman
- Joseph Konopelski
- *new* Sarah Loerch
- Scott Lokey
- John MacMillan
- *new* Shaun McKinnie
- Glenn L. Millhauser
- Carrie Partch
- Jevgenij Raskatov
- Seth Rubin
- Laura Sanchez
- Nick Sgourakis (now at University of Pennsylvania)
- Jin Zhang
We interact with the other five core facilities hosted by our department: cryoEM (RRID:SCR_021755), mass spec, NMR, X-ray, EPR, and a macromolecular structure and function core (for liquid handling and crystal maker, circular dichroism, isothermal titration calorimetry, Bio-Layer Interferometry, and X-ray crystallography).
Watch a slide show about 5 of the core facilities that the Chemistry department offers.
Listed alphabetically:
- Manny Ares
- Grant Hartzog
- Melissa Jurica
- *new* Sofie Salama
- *new* Shaheen Sikandar
- Bill Sullivan
- Olena Vaske
We interact with the CRISPR Core (RRID:SCR_021207) and Microscopy Facility (RRID:SCR_021135) hosted by the MCD department. Your drug screen may benefit from creation of knockout cell lines. And if you see an interesting phenotype in your cells with our screening microscopes, you can look at them with more color channel flexibility and potentially higher resolution (but lower throughput) using their light microscopes. They also offer Transmission Electron Microscopy for a finer detailed look at the cells.
Listed alphabetically:
Listed alphabetically:
The Banana Slug Genomics Center (RRID:SCR_021360) provides bioinformatics support primarily for sequencing data, but can also support analysis of data collected at the CSC! We interact with other core facilities at the Baskin School of Engineering, including the Flow Cytometry Facility (RRID:SCR_021149) and cell culture facilities (RRID:SCR_021353). We may also interact with other Engineering facilities, including the W.M. Keck Center for Nanoscale Optofluidics,
Listed alphabetically:
- Elizabeth Jones, College of Botanical Healing Arts
- Nevan Krogan, UCSF
- Roger Linington, Simon Fraser University
- Julian Sage, Stanford
- Nathan Shapiro, California State University East Bay
- Frederick Valeriote, Josephine Ford Cancer Institute
- Pieter Dorrestein, UCSD
- Richard Payne, University of Sydney
- Robert St Onge, Stanford
- Taro Amagata, San Francisco State University
Listed alphabetically:
- Boston Myoceuticals
- Hexagon Bio
- Perlara
- Sirenas Marine Discovery
- Unnatural Products, Inc.
We are proudly part of a collection of many diverse core facilities on the UCSC campus. In addition to the cores listed in the above departments, we have the following related core facilities:
- Ecology and Evolutionary Biology Department
- the Paleogenomics facility
- the Ancient and Degraded DNA Processing Center (ADDNAP)
- Genomics Institute
- Institute of Marine Sciences
- Marine Analytical Laboratory
- the Plasma Analytical Lab
- Organic geochemistry lab
- Earth and Planetary Sciences
- a long list of core facilities, including:
- stable isotope lab (SiL)
- the Keck Isotope Lab
- the FE Scanning Electron Microscopy Facility
- Greenhouse
Listed alphabetically:
- Shelby Backman
- Julian Blaseio
- Walter Bray
- Jennifer Burke
- Richard Cathey
- Sasha Curtis
- Julia Davies
- Nadine Gassner
- Britney Hernandez
- Jake Kosarchuk
- Cayla McEwen
- Kirsten McGee
- Sean Nisam
- Alex Ragland
- Elizabeth Rocha
- Jordan Ruybal
- Rochelle Saxton
- Joshua Schwochert
- Jordan Titus
Our sponsors:
We receive ongoing support from the Santa Cruz branch of the California Institute for Quantitative Biosciences (QB3) and the UCSC Physical and Biological Sciences Division, which supplements user fees to keep our staff paid and our instruments running.