10 AM REGISTRATION
Coffee available in the Bojwani room. Come check out the vendor tables in the Rotunda: Perkin Elmer, Agilent/BioTek, and BioLegend.
10:30-12:30 MORNING SESSION
10:30 AM Land acknowledgement, Vicki Auerbuch Stone, Professor of Microbiology & Environmental Toxicology and CSC Associate Director. Click for more info about the land acknowledgement.
10:31 AM Welcome, Glenn Millhauser, Head of Chemistry & Biochemistry Department
10:35 AM Opening plenary, Scott Lokey, Professor of Chemistry & Biochemistry and Faculty Director of the CSC
“UCSC CSC – a Rich and Varied History”
11:00 AM Tools & technologies update, Beverley Rabbitts, CSC Director of Operations
“Welcome to a New Era at the Fully Revamped CSC”
11:15 AM Research in progress: Jaru Taechalertpaisarn, CSC user from Scott Lokey’s lab
“Discovery of Novel Active Macrocyclic Peptides Through Permeable-First Perspective”
11:30 PM Research in progress: Aswad Khadilkar, CSC user from John MacMillan’s lab
“Assigning Mechanism of Action To Natural Products In Multiple Biological Contexts Using Gene Expression And Phenotypic Screening Methods Established By The HIFAN Program”
11:45 AM Morning keynote, Maureen Hillenmeyer, Founder and CEO of Hexagon Bio
“From academia to biotech startup: Launching a drug discovery company using new approaches in computation and automation”
12:30-1:30 PM NETWORKING LUNCH AND POSTER SESSION
12:30-1:00 PM First session – Poster presenters with last names A-L:
Abrams, Cech, Dzhanbekova, Hosseinzadeh, Hug, Jacobson, Johnson, Khadilkar, Liang, Lohith
1:00 PM-1:30 PM Second session – Poster presenters with last names M-Z:
Morris, Mitchell, Mueller, Ngoi, Rabbitts, Rubbo, Sharma, Taechalertpaisarn, Wijeratne, Yang
1:30-3:30 AFTERNOON SESSION
1:30 PM Invited faculty talk: Phil Crews, Distinguished Professor of Chemistry & Biochemistry
“Sponge Derived Molecule Discovery, Adventures of The Three Amigos Using the UCSC CSC”
2 PM Research in progress: Cindy Liang, CSC user from Angela Brooks’s lab
“Pairing Phenotypic Assays with Direct RNA Sequencing to Understand U2AF1 S34F and Cigarette Smoke’s Functional Role in Lung Cancer”
2:15 PM Research in progress: Gerd Mueller, CSC user from Seth Rubin’s lab
“Mechanisms of cell cycle-dependent gene regulation”
2:30 PM Presentation from our sponsor, Robert Graves, Field Applications Scientist, Perkin Elmer
“Phenotypic profiling by Cell Painting and fast confocal imaging with the Opera Phenix Plus High-Content Screening System”
2:35 PM Expression of gratitude, poster prizes, and awards, Beverley Rabbitts and Scott Lokey
2:40 PM Afternoon keynote, Michelle Arkin, UC San Francisco
“Looking for the Middle Way – Innovation and Application in Academic Drug Discovery”
3:25 PM Closing remarks, Paul Koch, Distinguished Professor of Earth & Planetary Sciences and Dean of the Division of Physical & Biological Sciences
Our industry sponsors will have the following vendor tables available throughout the day for education and networking:
PerkinElmer High Content, reagents and supplies, automation, plate readers, and bioinformatics (3 tables).
BioLegend Antibodies, proteins, and kits (1 table).
Agilent BioTek liquid handling (1 table).
We also thank our symposium sponsors at UCSC: the Office of Research; the PBSci Division Dean’s Office; Department of Chemistry & Biochemistry; Department of Molecular, Cellular, and Developmental Biology; Department of Microbiology and Environmental Toxicology; and the Biomolecular Engineering department within Baskin Engineering.
We also would like to thank the following supporters of the Chemical Screening Center: the Santa Cruz branch of the California Institute for Quantitative Biosciences (QB3) and the UCSC Physical and Biological Sciences Division. We are grateful for their ongoing financial support for our daily operations, which supplements user fees to keep our staff paid and our instruments running!