Research in Progress Presentations at the 2023 CSC Symposium

Poster session 1

Ben Abrams, academic/research staff – Life Sciences Microscopy Center. The UCSC Life Sciences Microscopy Center Has Tools for Your Research
Nadia Dzhanbekova, graduate student – Seth Rubin. Chemical Library Screening to Identify Novel Molecular Mechanisms Behind Cell Cycle Arrest
Sahar Hosseinzadeh, graduate student – John MacMillan. Identification of Selective Cytotoxins for Non-Small Cell Lung Cancer Cell Lines
Karen Hug, graduate student – Victoria Auerbuch Stone. Disruption of the Yersinia pseudotuberculosis T3SS primes bacteria for envelope stress
Rachel Jacobson, Senior Director Research – Spring Discovery. Using Machine Learning to Harness the Complexities of Inflammasome Biology for Novel Drug Discovery
*Aswad Khadilkar, academic/research staff – John MacMillan. Assigning Mechanism of Action To Natural Products In Multiple Biological Contexts Using Gene Expression And Phenotypic Screening Methods Established By The HIFAN Program
*Cindy Liang, graduate student – Angela Brooks. Pairing phenotypic assays with direct RNA sequencing to understand U2AF1 S34F and cigarette smoke’s functional role in lung cancer
Akshar Lohith, PhD Candidate – Scott Lokey and John MacMillan. Advancing Cell Profiling to cover a broad phenotypic space and determine the mechanism of action of diverse perturbations

Poster session 2

Gabe Mitchell, industry. Open Innovation @ NITD: targeting the host-pathogen interface during microbial infection
Joseph Morris, lab of Tyler Johnson, Dominican University of California. In Vivo Evaluation of Zampanolide & Thermolysis Reveals Cytotoxicity of Hemi-Aminal Side Chain & Delayed Binding Mode of Dactylolide
Samuel Mussetter, undergraduate student – Crews Lab. Further Evaluation of a Bicyclic Pyrazolines as a 15-Lipoxygenase V-Type Activators – Scrutizining Their 3D Properties
Peter Ngoi, graduate student – Seth Rubin. Structural basis for E2F1 Recognition by E3 Ligase SCF-CyclinF
Beverley Rabbitts, core director of CSCHigh content screening and machine learning for identifying novel natural product modulators of the innate immune response.
Francesco Rubbo, industry researcher – Spring Discovery. A Benchmark Dataset for Phenotypic Compound Similarity in Inflammasomes Screens
Diksha Sharma
, graduate student – Carrie Partch. Small-molecule screening:PASsing the binding test
*Jaru Taechalertpaisarn, post-doc – Scott Lokey. Discovery of Novel Active Macrocyclic Peptides Through Permeable-First Perspective
Tilini Wijeratne, graduate student – Seth Rubin. B-Myb association with DNA is regulated by its Negative regulatory domain and Cdk phosphorylation
Kevin Yang, graduate student – Scott Lokey. Development and Characterization of Passively Cell-Permeable RNA-Binding Cyclic Peptides

*=giving a talk (plus or minus poster) with this title. The rest are posters only.

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